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HIV-Glasgow 2018 – Fostemsavir (BRIGHTE phase 3 study): 48-week subgroup analysis

Conference Reports
05 november 2018

Dr Peter Ackerman presented the recent results of the BRIGHTE study – an analysis of the prodrug fostemsavir as an attachment inhibitor against HIV. Metabolism to the active moiety temsavir is via the gastrointestinal tract and it has been designed specifically for HIV-1 infected heavily treatment-experienced patients (HTP) who are failing their current therapy. In the BRIGHTE study, 86% of patients coming into the trial had a prior history of AIDS.

HIV-Glasgow 2018 – HIV-associated tuberculosis: diagnosis, management, and prevention

Conference Reports
05 november 2018

Dr Graeme Meintjes presents an overview of diagnostic and prevention issues in adult patients with HIV-associated tuberculosis. Estimates for 2017 showed that approximately 10% of global TB cases occurred in HIV infected people. This group also displays a disproportionately high TB mortality rate. However, incidence rates of HIV-associated TB have declined over the last decade.

HIV-Glasgow 2018 – Ibalizumab phase 3 trial: week 25 and week 48 analysis

Conference Reports
05 november 2018

Dr Zvi Cohen presents the phase 3 trial results of ibalizumab in heavily treatment experienced adults with multidrug-resistant HIV-1 infection failing their current ARV regimen; ibalizumab was approved by the FDA in March 2018 for this patient population. Results from the Week 25 study (TMB-301) along with the Week 48 expanded access (completer) study (TMB-311) are discussed.

HIV-Glasgow 2018 – MK-8591 efficacy against diverse HIV-1 subtypes and NRTI-resistant clinical isolates

Conference Reports
05 november 2018

Dr Jay Grobler presents the latest data on MK-8591, a novel nucleoside with a unique mechanism of action. This first-in-class nucleoside reverse transcriptase translocation inhibitor (NRTTI) inhibits HIV replication through multiple mechanisms.

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HEPATITIS C CHANNEL

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ATHEROSCLEROSIS GLOBAL ACADEMY

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Kongress Rapporter

HIV-Glasgow 2018 – Fostemsavir (BRIGHTE phase 3 study): 48-week subgroup analysis

HIV-Glasgow 2018 – HIV-associated tuberculosis: diagnosis, management, and prevention

HIV-Glasgow 2018 – Ibalizumab phase 3 trial: week 25 and week 48 analysis

HIV-Glasgow 2018 – MK-8591 efficacy against diverse HIV-1 subtypes and NRTI-resistant clinical isolates

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